Other several factors like damage to taste progenitor cells and disruption of gut microbiota are also dealt with relation to taste perception in cancer. We highlight the role of radio- and chemotherapy in the modulation of taste physiology. We also address the question of the implication of inflammation, responsible for the alterations in taste modalities. In this review, we summarize the mechanisms of taste perception and how they are altered in cancer. The change in taste perception might lead to malnutrition that is usually one of the frequent causes of morbidity and mortality in patients with cancer. The sense of taste is responsible for the detection and ingestion of food to cover energetic requirements in health and disease. 3Département de Biochimie, Biologie Cellulaire & Moléculaire, Université de Constantine 1, Constantine, Alegria.2UMR U866 Institut National de la Santé et de la Recherche Médicale/Université de Bourgogne-Franche Compté, Chimiothérapie et Réponse Anti-tumorale, Dijon, France.1Physiologie de la Nutrition and Toxicologie, UMR U866 Institut National de la Santé et de la Recherche Médicale/Université de Bourgogne-Franche Compté/Agro-Sup, Dijon, France.Khan 3, François Ghiringhelli 2 and Naim A. Babar Murtaza 1, Aziz Hichami 2, Amira S.
